Everyday life
Does Wegovy need to be refrigerated?
Yes, at 36°F to 46°F. If needed, a single dose pen or syringe can stay at 46°F to 86°F for up to 28 days, cap on. A started FlexTouch pen keeps 56 days in or out of the fridge. Never frozen.
The Oolite team, from the FDA labels
Sources checked Oct 27, 2026
Published Nov 8, 2026
Updated Oct 27, 2026 · 3 min read
The short answer
Yes, at 36°F to 46°F. If needed, a single dose pen or syringe can stay at 46°F to 86°F for up to 28 days, cap on. A started FlexTouch pen keeps 56 days in or out of the fridge. Never frozen.
What the label says
Wegovy comes as a single dose pen, a single dose syringe, or a FlexTouch pen that holds four doses. They share one rule and differ on the rest. The shared rule, from §16:
From the labelDo not freeze WEGOVY and do not use if it has been frozen.
For the single dose pen and syringe, the same section gives the fridge and the one exception:
From the labelStore the WEGOVY prefilled single-dose pen or single-dose syringe in the refrigerator from 2°C to 8°C (36°F to 46°F). If needed, prior to the pen or syringe cap removal, the pen can be kept from 8°C to 30°C (46°F to 86°F) up to 28 days. Protect WEGOVY injection from light.
The Medication Guide turns that into a list of when to throw it away:
From the labelThrow away the WEGOVY single-dose pen or syringe if it has been frozen, has been exposed to light or temperatures above 86°F (30°C), has been out of the refrigerator for 28 days or longer, or after use.
For the FlexTouch pen, the clock is different, because the pen is used over several weeks:
From the labelAfter first use, WEGOVY FlexTouch single-patient-use pen can be stored for 56 days between 15°C to 30°C (59°F to 86°F) or in a refrigerator 2°C to 8°C (36°F to 46°F).
Two clocks, not one
The single dose pen and syringe have a 28 day allowance outside the fridge, before the cap comes off. It is meant for when you need it: a trip, a fridge that broke, a week away. The syringe instructions suggest a simple way to keep count:
From the labelRecord the date your prefilled syringe was removed from the refrigerator and dispose of it, if not used within 28 days.
The FlexTouch pen starts its 56 days at the first use, wherever it is kept afterwards. Unused FlexTouch pens stay in the fridge.
Where the documents differ
There is one gap between the documents. The prescribing information and the Medication Guide give the FlexTouch a room range of 59°F to 86°F after first use. The Instructions for Use that come with the pen give a narrower one:
From the labelAfter first use, store WEGOVY FlexTouch between 68°F to 77°F (20°C to 25°C) or in a refrigerator 36°F to 46°F (2°C to 8°C) for up to 56 days.
A pen kept between 68°F and 77°F, or in the fridge, satisfies both. If yours spent time outside that narrower range, your pharmacist can tell you which reading applies.
Heat, light and the car
All the documents ask to protect the medicine from light, which is why the single dose pens stay in their original carton until use. The FlexTouch instructions add one place to avoid:
From the labelDo not leave it in a car or other place where it can get too hot or too cold.
The label also warns against the coldest part of the fridge: not in the freezer, and not right next to the cooling element.
If you switch to the tablets
The Wegovy tablets have the opposite rule. They are not refrigerated: room temperature, 68°F to 77°F, in the original closed bottle until you take one. Someone moving from the shot to the pill changes more than the morning routine.
Oolite logs the day of each shot and its dose. It does not track how long a pen has been out of the fridge, so the date on the carton is still the best record.
Questions people ask
Can I travel with Wegovy out of the fridge?
The label allows the single dose pen or syringe to be kept at 46°F to 86°F for up to 28 days, in its original carton, before the cap comes off. Above 86°F, or after 28 days out, it is thrown away. The FlexTouch instructions also say not to leave the pen in a car.
My pen froze by accident. Can I still use it?
No. The label says do not use Wegovy if it has been frozen, and not to store it in the freezer or right next to the refrigerator's cooling element.
I left it on the counter overnight. Is it ruined?
Not by the label's rule, if the room stayed between 46°F and 86°F and the cap was on: a single dose pen may spend up to 28 days out of the fridge. Count those days from the first time it came out.
Can it go back in the fridge after a few days out?
The label does not say. It counts the time out of the refrigerator, up to 28 days, and does not describe putting a pen back. Your pharmacist can answer for your device.
Sources
- Wegovy prescribing information, Novo Nordisk, §16, revised 06/2026 · Single dose pen and syringe: refrigerator 36 to 46°F, up to 28 days at 46 to 86°F before cap removal, protect from light, original carton; FlexTouch: 56 days after first use at 59 to 86°F or refrigerated; do not freeze, do not use if frozen.
- Wegovy Medication Guide, Novo Nordisk, revised 06/2026 · Throw away if frozen, exposed to light or above 86°F, or out of the refrigerator for 28 days or longer (56 for the FlexTouch); tablets at 68 to 77°F in the original bottle.
- Wegovy FlexTouch Instructions for Use, revised 06/2026, and single dose syringe Instructions for Use, approved 05/2026 · FlexTouch after first use 68 to 77°F or refrigerated for up to 56 days; not in a car; syringe: record the date it left the refrigerator.
Sources checked Oct 27, 2026. This page is information, not medical advice: read the medical disclaimer, and talk to your prescriber or pharmacist about your own treatment.
Written by
The Oolite team, from the FDA labels
We make Oolite. Every answer starts from the FDA prescribing information, quoted word for word, and is rewritten when a label changes.
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